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Anne Dejean (Pasteur Institute): Role of SUMO on chromatin in innate immunity and cell identity
Date: Thursday, 24. October 2019
Start Time: 16:00

Anne Dejean from the Pasteur Institute, https://research.pasteur.fr/en/member/anne-dejean/

“Anne Dejean is Research Director at INSERM, Professor at the Institut Pasteur and Head of the Laboratory of Nuclear Organization and Oncogenesis/INSERM U993. She graduated from Pierre et Marie Curie University in Paris and earned her PhD in Pierre Tiollais’ lab at the Institut Pasteur in 1983. Member of EMBO and of the French Academy of Sciences, she has received the Gagna and Van Heck Prize in 2003, the L’Oréal-UNESCO for Women in Science Awards in 2010, the Grand Prix INSERM in 2014 and the Sjöberg Prize in 2018. She was awarded two ERC Advanced Grants, in 2011 and 2018.

A molecular biologist, Anne Dejean investigates the molecular and cellular mechanisms involved in the development of human cancers. She discovered that HBV may act as an insertional mutagen in liver cancer. Since then, Dejean’s team has contributed several pioneering concepts in the areas of nuclear receptors and tumorigenesis with their discovery that retinoic acid receptors (RAR) genes are mutated in human cancers.  
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Recent projects in her lab aim at understanding how SUMO on chromatin regulates cell identity and cell fate in normal and cancer states.

Location : ZMBH, INF 282 Seminar Room Ground Floor
Contact Frauke Melchior
DKFZ-ZMBH Alliance Colloquium